A comparison of two practical Nissan SUVs for Orangeburg drivers. Learn how the compact Rogue delivers superior fuel economy on I-26 commutes, while the midsize Murano offers more rear cabin space and a smoother V6 for longer highway trips. Both earn top safety ratings, but their strengths split based on your priority: economy or comfort.
Here's the short answer. If you're running I-26 to Columbia five days a week, the Rogue's fuel efficiency is hard to argue with. If you're hauling four adults to Lake Marion for the weekend and highway comfort is the priority, the Murano earns its keep in ways the Rogue can't quite match.
Used Nissan Rogue inventory at Nissan of Orangeburg shows up on our lot regularly in the 2022-2024 range. Both vehicles carry Nissan's Safety Shield 360 as standard equipment, and they share the same 1,500-lb towing capacity. After that, they split hard in almost every direction that matters to a real buyer.
The short version
- The Rogue gets up to 37 mpg on the highway (FWD); the Murano gets 28. That gap compounds fast on a Columbia commute.
- The Murano is a midsize SUV; the Rogue is compact. That means more rear shoulder room (58.8 in vs. 55.9 in) and a smoother, torquier V6 in the Murano.
- The Rogue holds more cargo at full fold: 74.1 cu ft vs. 67 cu ft for the 2022-2024 Murano.
- Both earned IIHS Top Safety Pick+ recognition. Safety isn't the tiebreaker here.
- Pick the Rogue if you commute or prioritize fuel economy. Pick the Murano if highway ride quality and cabin space for adults define your trips.
What's the Real Difference Between These Two Nissans?
Both are two-row, five-seat Nissan SUVs, and that's about where the overlap stops. The Rogue is a compact SUV built around everyday practicality and segment-leading fuel economy, while the Murano is a midsize crossover built around cabin refinement, highway presence, and the kind of V6 torque that makes merging onto I-26 feel effortless.
| Feature | Used Nissan Rogue (2022-2024) | Used Nissan Murano (2022-2024) |
|---|---|---|
| Class | Compact SUV | Midsize SUV |
| Engine | 1.5L Turbo I-3, 201 hp | 3.5L V6, 260 hp / 240 lb-ft |
| EPA Highway MPG (FWD) | 37 mpg | 28 mpg |
| EPA Combined MPG | Up to 33 mpg | 23 mpg |
| Cargo (seats up) | Up to 36.5 cu ft | 32.1 cu ft |
| Cargo (seats folded) | 74.1 cu ft | 67 cu ft |
| Rear Shoulder Room | 55.9 in | 58.8 in |
| Towing Capacity | 1,500 lbs | 1,500 lbs |
| IIHS Safety Recognition | Top Safety Pick+ | Top Safety Pick+ |
The Rogue wins on cargo volume when the seats are folded, which surprises a lot of shoppers. The Murano wins on rear cabin width, and you feel that on every trip longer than thirty minutes.
Does the MPG Gap Actually Matter for Orangeburg Drivers?
It absolutely does, and the specific math is worth walking through. The EPA rates the 2022-2024 Rogue FWD at 30 city / 37 highway and the 2022-2024 Murano at 20 city / 28 highway across every trim, which works out to a 9-mpg gap on the highway alone. Orangeburg sits about 40 miles from Columbia on I-26 and roughly 75 miles from Charleston. If you're making that Columbia run four or five days a week, you're spending meaningfully more time at a pump in the Murano.
So does the bigger tank cancel the gap? Not really. The Murano does carry a 19-gallon tank versus the Rogue's 14.5-gallon tank, so you fill it less often. You still buy more fuel per mile. The tradeoff is real.
Browse used Nissan Murano options near Orangeburg if highway comfort is your priority, and go in knowing what the fuel economy looks like. The Murano's 3.5L V6 puts out 260 horsepower and 240 lb-ft of torque, which is no minor step up from the Rogue's 201-hp three-cylinder. It feels smoother at 70 mph, and highway passing happens without planning ahead, at least on that open stretch of I-26. For students making weekend runs or commuters who value that low-effort highway feel, that counts for something.
See all pre-owned inventory at Nissan of Orangeburg to check current year availability across both models.
Cargo, Cabin Room, and Real-World Family Practicality
The counterintuitive part is that the Rogue, despite being the smaller vehicle on paper, actually hauls more. With the seats folded, the EPA-rated max cargo volume runs 74.1 cubic feet in the Rogue against 67 cubic feet in the 2022-2024 Murano. The Rogue's Divide-N-Hide cargo system (standard on SV and Platinum trims) lets you set the floor at two levels, which earns its keep when you're sliding sports gear or groceries under a privacy cover.
The Murano counters with more rear cabin width. Rear shoulder room in the Murano measures 58.8 inches against 55.9 inches in the Rogue. Nearly three inches doesn't sound dramatic until you've driven Orangeburg to Charleston with three adults across the back, and then it does. The Murano is simply a wider, more relaxed place to seat four on a longer trip.
Both vehicles carry Nissan Safety Shield 360 as standard equipment across the 2022-2024 range, including automatic emergency braking, blind spot warning, rear cross traffic alert, and lane departure warning. The IIHS awarded the 2022-2023 Rogue its Top Safety Pick+ designation, and the Murano carried that same recognition from 2021 through the final pre-redesign year. Safety's a draw here. What really matters is how much space you need and how far you're driving.
So Which One Should You Pick?
Pick the Rogue if you commute regularly on I-26, if you rack up more miles than the average family, if you want that EPA-rated 37-mpg highway figure working in your favor on every tank, or if you're a Claflin or SC State student putting real miles on a daily driver. The Rogue is also genuinely easier to slot into the tighter spaces around Orangeburg, thanks to a tighter turning radius than the Murano.
Go with the Murano if you're prioritizing those longer highway runs (Columbia, Charleston, a Lake Marion weekend), if you frequently carry three or four adults, or if you simply want a quieter, more premium interior feel without stepping into a full-size SUV. The Murano's V6 doesn't have to work as hard to cruise, and that shows in how relaxed the long stretches feel.
The Murano does come with one caveat worth stating plainly. The 2022-2024 generation ran unchanged since 2015. The platform was solid, but it's the older design, and Nissan fully redesigned it for 2025. So those used 2022-2024 Muranos are proven and well-understood, they're just not the newest generation.
Explore financing options at Nissan of Orangeburg when you're ready to take the next step.
Frequently Asked Questions
Is the used Nissan Rogue or Murano better for a Columbia commute?
For a daily I-26 commute from Orangeburg to Columbia, the Rogue is the smarter pick on fuel. The EPA rates the 2022-2024 Rogue FWD at up to 37 mpg highway versus 28 mpg for the Murano, and over 40 miles each way, that difference shows up at the pump again and again. The Murano's smoother V6 is a pleasure on that stretch, but the commuter math favors the Rogue.
Does the Murano have more cargo space than the Rogue?
No, not at maximum capacity. The 2022-2024 Rogue holds up to 74.1 cubic feet with the seats folded, while the 2022-2024 Murano holds 67 cubic feet. The Murano does give you more rear cabin width (58.8 inches of rear shoulder room against 55.9 inches in the Rogue), which makes it more comfortable for adult passengers on longer trips.

